PROLOTHERAPY, PROLOZONE & OZONE THERAPY

Prolotherapy

Targeted Tissue Repair with Prolotherapy

Prolotherapy is a regenerative injection treatment that stimulates the body’s healing response to strengthen ligaments, tendons, and joints. By injecting a mild irritant (called a proliferant) into injured tissue, it triggers controlled inflammation—jumpstarting collagen production and repair where the body needs it most.

At Regeneration Pittsburgh, prolotherapy is used to treat chronic joint pain, ligament laxity, and musculoskeletal imbalances without the need for surgery or prescription medication. It’s a powerful solution for long-term relief and restored function.

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COMMON QUESTIONS ABOUT PROLOTHERAPY

Prolotherapy is commonly used to treat ligament and tendon injuries, joint instability, and chronic musculoskeletal pain. It’s ideal for patients seeking non-surgical options for long-term healing.

A natural solution (proliferant) is injected into the injured area, triggering a localized healing response. This encourages the body to strengthen and rebuild weakened connective tissues.

Most patients see results in 3 to 6 sessions spaced a few weeks apart, but the exact number depends on your condition and how your body responds to treatment.

PROLOZONE therapy

Oxygen-Enhanced Regeneration

Prolozone Therapy builds on prolotherapy by combining the healing power of ozone (O₃) with a proliferant solution. This dual-action approach not only stimulates tissue repair but also increases oxygenation at the cellular level—essential for reducing inflammation and accelerating recovery.

Ideal for patients with chronic pain, degenerative conditions, or low tissue oxygenation, Prolozone offers a natural and highly effective option to restore function and mobility.

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Reduces Inflammation and Chronic Pain

Ozone helps neutralize oxidative stress and inflammatory buildup.

Enhances regenerative response

Combines oxygen therapy with collagen stimulation for deeper healing.

Common Questions About Prolozone Therapy

Prolozone includes all the benefits of prolotherapy, but with the added healing power of medical-grade ozone. The ozone increases oxygenation in tissues, which speeds healing and reduces inflammation.

Prolozone is particularly helpful for joint pain, osteoarthritis, soft tissue injuries, and slow-healing musculoskeletal issues where poor circulation or inflammation are contributing factors.

Yes—ozone has been used safely in medical applications for decades. Treatments are performed by trained providers and are well-tolerated by most patients.

Ozone Therapy

Fuel Your Healing with Ozone Therapy

Ozone Therapy uses medical-grade ozone (O₃)—a highly energized form of oxygen—to boost circulation, reduce inflammation, and support immune balance. This gentle yet powerful treatment is delivered via IV, nasal or ear insufflation, and often paired with our regenerative protocols. Once in the body, ozone enhances oxygen delivery to your tissues, improves red blood cell function, and activates antioxidant pathways. It’s an ideal option for those managing chronic illness, low energy, or inflammation—or anyone looking to optimize their overall health.

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Modulates immune response naturally

Calms overactive immune systems and boosts underactive ones for balanced immunity.

Boosts energy, performance & overall recovery

Increases endurance, supports detoxification, and promotes full-body resilience.

Common conditions supported by IV Ozone Therapy include:

Ozone Insufflation

Ozone insufflation is a safe and non-invasive method of introducing medical-grade ozone into the body to support healing, reduce inflammation, and enhance immune function. At Regeneration Pittsburgh, we offer two targeted options—ear insufflation and nasal insufflation—designed to deliver localized therapeutic benefits for sinus, ear, and neurological health.

Nasal Insufflation

Bubbled through olive oil, you can safely breathe ozone gas to help inflammation and illness in your lungs and sinuses. 

Best used in a series of 1-3x weekly for symptom control.

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Close-up of a water droplet on a green leaf with a dark background Close-up of a water droplet on a green leaf with a dark background

Ear Insufflation

Ozone gas applied to the ear canals to rid inflammation and drainage of the ear and sinuses due to infection.

Best used weekly or 3x week for symptom control.

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common questions about Ozone Therapy

Ozone therapy uses O₃, a highly energized form of oxygen, to stimulate healing at the cellular level. It improves circulation, reduces inflammation, and helps regulate the immune system—making it effective for a wide range of health concerns.

Yes. When administered by trained medical professionals, ozone therapy is considered safe and well-tolerated. It has been used for decades in integrative and regenerative medicine with minimal side effects.

Treatment frequency varies by individual and condition, but most patients benefit from a series of sessions, often 1–3 times per week. Your provider will personalize a plan based on your goals and response.

Absolutely. Ozone is often used alongside other regenerative therapies, IV nutrient infusions, or injection treatments to enhance overall outcomes and speed recovery.

YOUR WELLNESS REIMAGINED. ONE STEP AT A TIME.